Increase Mental Performance and Reduce Stress in Adults and Children and Athletes

Phosphatidylserine effectively reduces physical and mental stress in young persons. (191)

Phosphatidylserine significantly improves ADHD symptoms and short-term auditory memory in children. (217)

Human clinical trials on physcial and mental stress show that phosphatidylserine supplementation in in Flavay Plus® is not just helpful for elderly, but young adults and children, too.

Phosphatidylserine is considered to be one of the most important brain nutrients beneficially influencing numerous neurotransmitter systems, such as acetylcholine, dopamine, serotonin and norepinephrine. Phosphatidylserine in Flavay Plus® has been shown to counteract the stress-induced activation of the hypothalamic-pituitary-adrenal axis when faced with a physical stressor. (216)

In young healthy college students, phosphatidylserine supplementation in Flavay Plus® resulted in an increase in mental performance during a calculus test and an increase in accuracy off the tee and a reduction of perceived stress in golf players. (216, 215)

A pilot study on 15 ADHD children, ages 6–12 years, shows that the administration of 200 mg of phosphatidylserine per day for 2 months significantly improved ADHD symptoms. (218)

Recently, a randomized, double-blind, placebo-controlled trial performed on 36 children (ages 4 to 14) confirmed previous findings. Phosphatidylserine is helpful for children with behavioral and attention problems.(217)

Double-Blind, Placebo-Controlled, Crossover Studies

Scientific Trial Description Author, Year of
Publication (Ref.)
(mg per day)
A randomized, double-blind, placebo-controlled study performed on 36 children (ages 4 to 14) who had not previously received any drug treatment related to ADHD. Main outcome measures included: (i) ADHD symptoms based on DSM-IV-TR; (ii) short-term auditory memory and working memory using the Digit Span Test of the Wechsler Intelligence Scale for Children; and (iii) mental performance to visual stimuli (GO/NO GO task). Results: “Phosphatidylserine significantly improved ADHD symptoms and short-term auditory memory in children. Phosphatidylserine supplementation might be a safe and natural nutritional strategy for improving mental performance in young children suffering from ADHD.” Hirayama S, et al., 2014 (217) 200 60 days
Double-blind, placebo-controlled, crossover study on healthy young men (about 26 years old) found: “phosphatidylserine is an effective supplement for combating exercise-induced stress and preventing the physiological deterioration that can accompany too much exercise. Phosphatidylserine supplementation promotes a desired hormonal status for athletes by blunting increases in cortisol levels.” Starks MA, et al., 2008 (216) 600 10 days
Placebo-controlled studies where phosphatidylserine significantly blunted the rise in cortisol caused by physical stress in healthy young men. Monteleone et al., 1992 (117) 800 10 days
Fernholz et al., 2000 (120) 600 or 300 15 days
Fahey et al., 1998 (121) 800 14 days
Double-blind, placebo controlled clinical trial on young healthy university students subjected to standard acute stress test: mental arithmetic under time pressure. Stress was monitored by heart rate. Students taking phosphatidylserine scored significantly better, were more clear-headed, confident and composed. Benton et al., 2001 (191) 300 30 days
A randomized, double-blind, placebo-controlled study performed to evaluate phosphatidylserine supplementation on golf performance in healthy young golfers with handicaps of 15–40. Results show a tendency to improve perceived stress levels and significantly improves the number of good ball flights during tee-off which might result in improved golf scores. Jager et al., 2007 (215) 200 42 days

Phosphatidylserine occurs naturally in the body and supplementation has proven very safe for adults and children.

Is Phosphatidyl
Serine Supplementation Safe?

Phosphatidylserine in Flavay Plus® is extracted from soy which is confirmed non-GMO. The phosphatidylserine in Flavay Plus® was the subject of many human clinical trials regarding memory loss, mood, cognitive performance and learning ability.

The use of phosphatidylserine in Flavay Plus® is well validated through clinical research and proven safe in standard toxicology tests.

The large number of human studies conducted on phosphatidylserine in Flavay Plus® produced a flawless safety record. First, it has proven compatible with a wide array of medications including: antacids, anti-hypertensives, anti-inflammatories, anti-ulcer and mucolytic agents, diuretics, anti-thrombotics, hypoglycemics, anti-arrhythmics, insulin, calcium channel blockers, calcitonin, chemotherapy drugs and other prescription medications. Second, phosphatidylserine is well tolerated by elderly patients with chronic diseases such as cerebrovascular, artery and vein disorders, heart diseases, high blood pressure, diabetes, lung diseases, digestive system diseases and arthritis.

Interestingly, clinical researchers found phosphatidylserine lowered uric acid levels and liver SGPT in their elderly patients—which can signify improved liver health. (106,110,114-117,119) More →

Authentic vs. “Borrowed” Science

Not all phosphatidylserine products are equal. The marketplace is full of inferior variations of scientifically proven natural products. Those who are looking for a product that will produce the proven results and not just “claimed” or “implied” results want authentic products proven in scientific research.


Consumers want phosphatidylserine that is proven safe and effective. Both phosphatidylserine in Flavay Plus® and Flavay® are proven in clinical trials. Flavay® was also patented as a “free-radical scavenger.”

Phosphatidylserine in Flavay Plus® is extracted from soy which is confirmed non-GMO.

Synergistic Results in
Clinical Strength
Cost-Effective Capsules

Confirmed NON-GMO

Flavay Plus PhosphatidylSerine buy now
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